EP Edge Journal Watch Issue 13 (March 2026): Ultrashort AF, ILR Accuracy, Semaglutide + Ablation, PADIT, PCOS, LBBAP and Next-Gen nanosecond PFA (SCENA-AF)

EP Edge Journal Watch — Issue 13 (March 2026) explores a core 2026 EP problem: signal detection (wearables, patches, ILRs) and energy delivery (next-gen PFA) are advancing faster than the clinical rules we use to interpret risk and outcomes . In this episode, Dr. Niraj Sharma breaks down what’s clinically actionable, what’s methodologically fragile, and what should change practice now versus what needs better evidence. Topics covered (high-level): Ultrashort atrial arrhythmias ( and what they may imply on continuous monitoring Implantable loop recorder (ILR) “AF alerts” and why vendor performance is not interchangeable Semaglutide (GLP-1) and AF ablation in obesity: metabolic modulation as an EP strategy, not an afterthought Nanosecond pulsed field ablation (nsPFA) for paroxysmal AF ( SCENA-AF ) and what it means for workflow (including anesthesia strategy) A high-stakes coronary spasm signal in a population-enriched cohort LBBAP perforation detection: interpreting iEGMs as phenotype, not just amplitude PADIT score validation by infection subtype—toward phenotype-aware prevention PCOS and long-term arrhythmia risk: a women’s cardiovascular EP domain hiding in plain sight Read the full newsletter (graphics + references): epedge.substack.com Subscribe on LinkedIn (EP Edge Journal Watch): https://lnkd.in/e-Wa4diC Subscribe to EP Edge (Monthly Deep Dives): https://lnkd.in/ep3NdZUz Subscribe Substack: epedge.substack.com