WEEK 6 PICKS: Seahawks or Broncos? Eagles or Panthers? Packers or Cowboys? Bears or Falcons?

NFL's top seeds clash as the Seattle Seahawks face the Denver Broncos in a Week 6 kickoff packed with storylines. Can Denver's struggling offense challenge Seattle's defense, especially amid a vibrant '90s throwback uniform showdown at Mile High? Joe Marino and Kyle Crabbs debate key matchups, highlight Jacksonville Jaguars' London dominance, and explore the impact of home-field quirks and roster injuries across the league. Bold predictions fly, with intriguing picks for the Bears-Falcons showdown as Caleb Williams looks to rally Chicago and the Patriots eye a statement game against the Jets. The episode covers the Giants' upset chances over the New Orleans Saints, critical injuries to the Philadelphia Eagles, and offensive mismatches in Chiefs-Chargers. Plus, insights on Jonathan Taylor's workload for the Colts, James Cook’s breakout potential for the Bills, and whether the 49ers' growing injury list puts their commanding NFC run at risk. Photo Credit: Joe Nicholson-Imagn Images Support Us By Supporting Our Sponsors! Gameday Men's Health Book your complimentary test and consult at https://join.gamedaymenshealth.com/reasons_to_choose_gameday-1201?utm_source=lockedon&utm_medium=podcast&utm_campaign=NFL&utm_network=lockedon&utm_adgroup=corp&ghl_tag=national,corp Odoo Great organizations win because operations matter. And that’s why you should get Odoo. Try for free today at https://Odoo.com/lockedon . Butcher Box If you're looking for an easier way to get great meals on the table, give ButcherBox a try. Go to https://ButcherBox.com/LOCKEDONNFL to get $20 off your first box, plus your choice of free ribeye, new york strip, or filet mignon in every box for a year — with free shipping always. Apple You can earn up to 3% unlimited Daily Cash back on every purchase you make with Apple Card using Apple Pay. Apply in the Wallet app on your iPhone today. Subject to credit approval. Apple Card issued by Goldman Sachs Bank, USA. Salt Lake City Branch. Terms and more at apple-card-dot-com. https://learn.applecard.apple/unlimited-daily-cash?cid=apy-318-2000008800000-400000000000039&itscg=2030032&itsct=srvs-crd-P3004756-C3004897&mttnagencyid=c1a&mttnsiteid=133087&mttnpid=LockedOn%20%28Audio%29&mttnsubad=srvs-crd-P3004756-C3004897&mttnsubplmnt=&mttncc=US PrizePicks Visit https://prizepicks.onelink.me/LME0/LOCKEDONNFL and use code LOCKEDONNFL and get $150 if you win your first $5